Genetic counseling for clients

Genetic counseling for clients

DNAnutriControl (PACK-NM-LS)

Training video

Take your booklet at hand and let a geneticist explain your genetic analysis. Learn also how to properly use the program. Additional advice for the DNAnutriControl program.

Spoken text of the video

Section 1: Intro

y name is Daniel Wallerstorfer, I am the Scientific Director of the laboratory your genetic test was performed in and I would like to take some time to go through your genetic test with you. So I would like to ask you to take your report, no matter if it’s a hard copy or a digital copy and then we’re just going to start from page number one. I am going to have a digital copy of the report on my screen and we just go through it step by step. And this should ensure that you understand everything correctly and that you also know how to use the report, because there is no use in knowing about your genetic information if you don’t know how to use this information to your benefit.

Section 2: The Genetic Code

Alright. By the way do take note : This might be a slightly older video by the time you’re watching it and we continue improving our reports, so there might be some differences between what I have in my screen and what you have in your booklet, so don’t worry if there are some differences, I will explain the general concept and I am sure that you’re going to understand what I am trying to say even if there are minor differences. And also there are different versions of this report. Some are specifically tailored for sport studios and some are specifically tailored for use with doctors, so there might also be minor differences but then, again this video is going to help you understand all of the aspects of the analysis. Alright. So the whole thing starts with the cover letter. Here you’re just going to find out some information of when has the genetic sample arrived to the laboratory, when we’ve performed it, and you’ll also find my signature releasing the results for report creation. And on the next page, I just have a table of content, and then we start here, so let me enlarge this a little bit. I would really recommend that you read through this once, it’s very easy to understand, I am sure you’re going to find it interesting but let me just quickly summarize what you find in this section. The human body consists of around fifty trillion individual cells, and every one of those cells, with minor exceptions, has a cell nucleus, and in the cell nucleus there are the human chromosomes and these are the x shapes that you see here. And if you take a closer look at the chromosome, you find that it is in fact a very tightly round thread and this thread is the DNA double helix. And this is the helix structure that you see. Now, if you look at the helix in more detail, you actually see genetic letters. In reality these are not really letters, but certain chemical structures that are there but scientists abbreviate them in genetic letters, A T G and C and those are the four different letters that our genetic code is made of. And this is incredibly much information. For example, if I were to read out the genetic code A T G A C GG in this speed of just one single cell, then it would take me one hundred years to complete it. And this is just one cell and as we’ve said we have fifty trillion individual cells. That’s incredibly much information.

Section 3: The genes

Alright. Now, what are the genes? Genes are certain regions in this genetic code and a gene contains an instruction. It’s an instruction to your body of how to do something. For example, the lactase gene, the LCT that’s the abbreviation. This gene means that in this genetic code there is the instruction for your body of how to produce an enzyme. An enzyme is kind of small scissors that can cut off, that can digest something. And this gene has the genetic information of how to build this enzyme and how to digest lactose, lactose is a milk sugar. There is another gene, the thrombosis gene, factor five. This just means that this gene here contains the information of how to prevent thrombosis, a blood clot, from forming in your arteries when it shouldn’t be the case. So, there is a gene that has a certain function and another gene that has another function and most genes mostly have only one function, some have a few but this is pretty much how the instructions of your human body look like. And there are twenty five to thirty thousand different genes. And there are different versions of each gene. So, there is a blue version of an eye color gene and a green version and so on. And this is the general concept of the human blueprint, of how to build a body structure.

Section 4: Genetic Variation

Now the next question is what is genetic variation? If you were to take my factor five gene and that of any random person, you put them next to each other, you would find that the code is almost identical. There are only going to be few situations, very few positions where there might be one letter change. So, the genes, virtually all humans have exactly the same factor five gene, but some have one letter in one position and some people have another genetic letter. And these genetic variations are called snips, Single Nucleotide Polymorphisms. So we don’t actually need to look at the whole gene because the genetic variations are usually, only part where there is a difference from one person to the next. So if we look at a certain letter here, it might be that if there is an A here, that means the gene works normally and if there is a G, the kind of genetic error, then the gene has lost its function, it forgot the instruction that it should encode. So, what we can do, we look at a specific genetic variation and we know if there is an A here, then you don’t have an increased risk of thrombosis, and if there is a G here then you do, because the gene does not function correctly. And that’s the general concept of genetics. Again, there is more information in here if you’re interested do read through it, it’s an interesting reading in my opinion. So the program is structured in such a way that you can use genetics to improve weight loss or use genetics to eat healthy or do both. There are different sections in the report depending on what you’ve ordered.

Section 5: The Nutrition Sensor

So this here is the nutrition sensor part. So this is the eating healthy part to make sure your body gets the right nutrients. And this is useful for preventions, so to prevent certain metabolic problems, to develop and for treatment. So if you have certain metabolic problems or you might even be a diabetic or something, if you mention that in or mentioned that in the order form the nutrition will be adapted to make sure you get the right nutrients that are necessary for your fliction. So, it’s meant to help you stay healthy and to improve your health if you already have some metabolic problems or disease problems. This page here is going to explain a little bit about nutrigenetics, how genes are going to influence one person differently than others because the general assumption that eating healthy is the same for everybody. You should eat a lot of food and low fat and low sugar. This is just too simple unfortunately, because for some people for example milk products are a very healthy source of calcium. So for them it’s good to eat milk products because they get a lot of calcium. Other people might be genetically lactose intolerant so they can’t eat milk products, so for them this is not true because if they eat milk products, they gonna have very bad digestive problems. So this is just one example, one gene and here we’re testing more than fifty genes, more than twenty different metabolic problems that arise through this, and each one of them has different nutrition needs that might vary from one person to the next. And this is the concept of nutrigenetics. We test the genes, find out what your personal needs are, what you should avoid, and then we make a list of types of food where we tell you this is good for you to eat and this is bad for you to eat. And by just following eating more of the good stuff, and eating less of the bad stuff, you will do the best you can to supply your body with exactly the nutrients that it needs and you avoid substances that you really can’t work with.

Section 6: Detoxification

Now detoxification is an interesting concept. Basically, there are a number of different toxins, toxic chemicals and stuff in our environment that that can get into our body, and nature knows about this. So we have a number of genes that can recognize these toxins, neutralize them, and remove them from the body. And as you can guess, it’s genes that are doing this, they are regulating this. And some people have variations in some of these genes, which means that they cannot neutralize some of the toxins while other people can. So there are big differences in how people respond to certain toxic chemicals and stuff.

Section 7: Detoxification Phase 1

Alright, let’s look at your results. So again on this page, you will find some general information to read through, and here is phase one of detoxification. And this is all about, ash, soot, smoke and burned things. So as you know smoking increases your risk of lung cancer that is because some of this smoke content are carcinogenic, they are cancer-causing, and they reach our body and then a certain enzyme system, genes, recognize these toxins, these carcinogens. They neutralize them and remove them. So we have a protection from this cancer-causing substance that reaches our body. So these two genes here are responsible for this detoxification. So I smoke a cigarette, the toxins get into my body, these two genes recognize the toxin and neutralizes it and prevent it from giving me cancer. And in this case both of the genes are defective, and they increase the risk. So we have two genes that give me risk. This one two point four fold and three point four fold, so we have run five to six fold higher risk of bad health effects from these toxins that a person can smoke in ash, in burned food, so on. Barbecue food also is much more of a problem for a person with this result because you see here that phase one of detoxification is ineffective and it might also be very effective, so in this case it’s not much of a problem. It still doesn’t mean you should smoke, it’s still dangerous to likely, to significantly shorten your lifespan but for this person it’s five to six times worse, more problematic, than for many other people. So, in case you are a smoker and I hope you’re not, and in case you’re smoking, here in this area, then you really should reconsider your habits because it’s five times more dangerous, more problematic for you than for many other people. It’s much more dangerous for your health than it might be for many other people. This also explains why sometimes people smoke for five years and develop lung cancer and others till eighty years old and never develop lung cancer, just because the bodies respond differently to these cancer-causing substances. Alright. So do check your own results. If you’re here that means barbecue food generally is not very healthy but it’s not much of a problem if you have charred or blackened part of the meat. You shouldn’t eat burned food anyhow. However, if you’re here it’s a lot less healthy for you and you should really try to cook food in such a way that it is not getting charred or black.

Section 8: Detoxification Phase 2

This is the first step. This just tells that barbecue concept Yes or No. The second phase, phase two detoxification, is a lot more interesting. I am sure you’re aware of this trend of organic food, meaning that the food was grown without any chemicals, without pesticides, herbicides and so on. Now some people say this is very healthy, because all of these chemicals are unhealthy for you. Other people say they don’t matter, they’ve been tested they are not dangerous. In a way both of them are right, because phase two of detoxification, let me zoom in here, these three genes are responsible for phase one of detoxification. And this means if I eat some vegetables that have a lot of herbicides in them, then the vegetables are going to contain these three substances. They are going to reach the body and then there are these three genes which produce enzymes which recognize it, neutralize it and remove it. So, it’s not a problem. The same goes for industrial solvents and things like that. For other people, however, they might not have some of these genes active. And in this case, the herbicide reaches the body, it’s not recognized, it’s not removed and it can do its damage. So for some people absolutely it is a problem, because they cannot neutralize the toxins that reach the body. For other people it’s less of a problem. It’s probably still unhealthy, but it’s definitely not such a big health risk and health issue than for other people. Let me just quickly talk you through the results here. Here we see null allele which you might be interested in. You see here we have a category number, an rss number for the genetic variation where one letter change is happening, but here the null allele is something different. We don’t know why but some people, those who don’t have genetic variation that breaks the gene, but actually they missed the whole gene. The whole gene is gone and that is called null allele, allele being one copy of a gene. So you can have two missing copies of the gene. You can have one copy and one missing copy or you can have two copies of it. And in this case this is the optimal genetic result. Do check what your result is. And you see here the effectiveness of phase two detoxification is very effective. It might also be very ineffective or somewhere in between. Now if you are in the effective area, then organic food might still be a good idea, but it’s not going to be so critical for you. If you’re here I would really make sure that I eat organically, try to avoid any kind of substances, fertilizers that might contain substances that could harm your body. Now the same goes for heavy metals. Lead for example is a heavy metal, that’s very unhealthy. Many people, some people get lead toxification. And the same goes for cadmium and mercury. And these substances for one thing accumulate in some certain types of food like shellfish. Now, it’s not a problem for many people, because they, the genes, recognize them and remove the heavy metals, for other people they can’t remove them. They might accumulate in the body, and start damaging the person’s health. So depending on your results here, we’re going to see if shellfish or fish generally fish grown, found in the sea, are also more polluted with heavy metals. These might be less recommended to you, based on your detoxification capacity, or it might be very healthy for others. So just for fish we already have two things now; the content; good or bad or also the content of pollutants that are common in this fish.

Section 9: oxidative stress

Alright. Do check your results. Ineffective means organic food, less fish, less shellfish and here all of this is not much of a problem. So ok, that’s phase two of detoxification. Then we have oxidative stress and you will likely have heard about this before and oxidative stress is a by-product of converting energy in our body. When we use oxygen, we need oxygen to convert energy and do something with it, run our body. And the by-products of this metabolism are free radicals and they’re kind of small toxic molecules that are created and they then grab onto something and break it and this grab onto something else and break it and this grab onto something else. So this is sort of a chain reaction of damage until an antioxidant, it’s a free radical inhibitor, a free radical captor we can say, comes along and grabs it and stops this chain reaction. And this happens throughout our body or in many different ways. So lots of different types of free radicals and they damage our tissue. And they have something to do with ageing, ageing of the skin and just getting older. They’re just one of the main parts that are involved in this. So free radicals are continuously produced and they damage the tissues and eventually the damage accumulates and the skin begins to sag and you become more prone to disease. Now since nature knew that, this genetic variation is so dangerous, sorry these radicals are so detrimental to health, we have a number of safeguards and these genes here have these roles. These genes protect us in different ways from these free radical inhibitors, from these free radicals. Alright, so you can read through this and will explain it in a bit more detail and now let’s look at scale bars which is an important thing. So, generally, your oxidative stress, how well you are protected from these age-promoting free radicals, normal means good protection, your genes are working, they’re protecting you, increased means your genes, at least some if not all of the genes are disabled through some of the genetic variations and you don’t have the protection that other people would have from these free radicals. Then the recommended dose of antioxidants, I said these free radicals do the damage until an antioxidant radical inhibitor comes along and grabs onto it and neutralizes it and these antioxidants free radical inhibitors are vitamin C, vitamin E, vitamin A, Alpha lipoic acid and some other substances. So, mainly of the typical vitamins that you’ve heard about they are healthy, some of them do neutralize free radicals. So, on the one hand you have genes that protect you but they might be broken, and on the other hand you have these vitamins that can protect you. If the genes are broken, you gonna need more vitamins to counteract this lack in protection. And that’s the basic concept. You test your stress, how good your genes are, if they’re good you need a few vitamins, if they’re bad because they’re broken, you lack this protection, and then we’re going to get different types of food that contain a lot of these vitamins and we’re going to recommend more to you in your nutrition plan, because they contain antioxidants. Vitamins are very important for you to remain healthy. So, again your genes tell us how important some substances in some foods are for you.

Section 10: Coenzyme Q10 and ubiquinol

Alright. The next question, Coenzyme Q10 and ubiquinol. This is a very interesting story. If you use skin creams you might have realized that some skin creams use coenzyme q10 as a component, because coenzyme q10 has the potential to be converted to ubiquinol. So q10 is not active, ubiquinol the active form can neutralize free radicals and slow ageing. That’s the concept. And that’s in all skin creams and all sorts of beauty products. Some people also take it as a nutrition supplement. A pill and it’s swallowed, it reaches the body, it’s converted to ubiquinol and protects you from oxidative stress. However, as I said you need to convert it because q10 by itself is not active, and there is a gene that produces an enzyme, scissors kind of, that recognizes q10, modify it, and then you get ubiquinol. And this ubiquinol is an active. So q10 itself is inactive, and you might have guessed it, there is a genetic variation that disables the enzyme. So what happens is I take the q10, it reaches my body, then there are no scissors, no enzymes modifying it, there is no action and I take it every day because I want a lot of protection from oxidative stress and it’s a very expensive supplement as well, and instead of benefiting from it, I lack this function and it’s not active for me. So there are two ways we can do in this case. You can either already take the activated form, ubiquinol, or you can counteract it with all of the other antioxidants, vitamin C E A and all of these substances. So, you take more of them, you can partly balance that you’re lacking this function. So here, you’re going to find out if your body is able to activate coenzyme q10 to ubiquinol. If it’s possible, coenzyme q10 is going to be active, is going to help you. If it’s here, then it’s useless, then some of you will now probably find out that you’ve taken coenzyme q10 for years and you cannot process it, and it was all for nothing. And here you see the recommended dose of antioxidant substance, coenzyme q10 or alternative vitamins depending on where you are. And again we can take this information and we will find whether you need more vitamins or not, and then we choose which type of food to recommend you. And then selenium. That’s also a very interesting story. Selenium is a trace element that is contained within food. And there is a gene, the GPx1 gene, actually let me scroll up here, actually the gpx1 gene is this one here. This gene protects you from free radicals as well. And it works like this. The gene has instructions for an enzyme that has a function to float around and grab onto free radicals and neutralize them. However, for this enzyme to work, it needs selenium. Selenium is an integral part of how to build this thing, one of the building blocks. So, if a person is selenium deficient, that’s too little selenium, through poor nutrition, they’re going to produce the enzyme but it’s not gonna work. And only some of them will work. The actual function of this protective enzyme is very low, that is why it’s unhealthy to be selenium deficient, one of the reasons. If then you increase the amount of selenium through healthy nutrition, or maybe a supplement for selenium, you can recover this function, because the new enzymes are being built correctly and they can do this function and they protect you from these free radicals. Now there is a genetic variation that’s not very common, that messed up the building structure for this enzyme, so it’s still building it kind of correctly, but it’s slightly modified. So it grabs onto free radicals less efficiently. So even with normal selenium status this doesn’t work very well. So you have lower protection from free radicals because of this genetic variation. And now the interesting thing is, scientific studies have found out, if you increase the amount of selenium too far above normal levels, you can rescue the function of many of these and then you can increase the protection again. So, this is a very interesting point, some people say why do the genetic test to find out how much selenium a person needs while I do a blood test, check out if they are in a healthy range, if yes fine, if not we give them more selenium. But that’s exactly the point, if the gene works normally, which you can only test through genetics, the normal range is ok, but if the gene has a genetic variation, you need much more, much higher than the normal range to achieve the same result. So through genetics we know you should be in a higher range, you should be in a low range, while a blood test would say this is a healthy range which we try to put everyone in, and we just judge everyone to be in the healthy range. So really there are some things which a blood test can do, which genetics can’t, like see if there is a deficiency, genetics has no chance to do this, but genetics has the option of finding out how much should we have because not everybody’s requirement is the same, as we’ve seen in this gene. So, by looking at this gene, we know your requirement of selenium. If it’s increased, like in this example, it means that the genes are modified, it’s less effective, and you can rescue some of the functions with more selenium and it you’re here at the normal range, normal amount of selenium is completely sufficient for you. So again, what we do is look at this we find out how high requirement of selenium is, and then we evaluate every one of the one thousand different types of food and we can find this has a lot of selenium, you need a lot of selenium, so we’re going to recommend this type of food more.

Section 11: Ingredients Evaluation

Alright. So by testing more than fifty genes we now know the different tendencies that you have different metabolic problems that might occur from these genetic variations. We know what sort of substances in food that might be beneficial for your health, which might be detrimental to your health, and we can tell this is good or this is bad for you. And here is a summary. So again do read through this so just to explain food ingredients. Now there are a number of good and bad substances in food that we are evaluating here. So if you check this page here, total fat, a lot of fat is generally bad for people, but for some people it’s moderately bad and for some it’s extremely bad because of genetic variation. They just respond to it more and they have more negative health effects from it. So do check where your arrow is. In this case, it’s very unfavorable. Saturated fatty acids, that’s the unhealthy type of fat so unfavorable. Cholesterol also unfavorable in this case. Total sugar, a lot of sugar and high calories from sugar is also bad for this person. Glycaemic index is not so bad, glycaemic index is how fast the sugar goes into your blood stream and then it might increase a lot, a lot very quickly so it spikes which is bad for some metabolic problems, and it should be avoided for some genetic types and it’s not much of a problem for other genetic types. So having a high glycaemic index is not so much of a problem here, it might be much worse for you. Sodium, stable salt, for some people is normal, for others it’s very unhealthy. Amino acids, cysteine and methionine in this case are very unfavorable. It might be different again in your case. Then phosphorus which is in chocolate, in meat products, sausages and so on is moderately unfavorable. Arachidonic acid, this is something in animal products, it increases the inflammation response of the body, is moderately bad, it might be very bad for you or normal. Alpha linolenic acid and EPA are under the free fatty acid, they are for some people favorable, for some medium and for some unfavorable, it’s unfavorable in this case. Then alcohol is very unfavorable, coffee favorable in this case, it can have a protective effect as well, it has a lot of antioxidants, so for some people it’s good, and purines again are moderately unfavorable. So this is just some background information. These are the typical substances in food that are bad for you, very bad for some, moderately bad for others and some of them are good for you.

Section 12: Micronutrients

And then there are also the micronutrients, the vitamins, the minerals and so on. And through your genetics we can find out how your body responds to many of these vitamins and minerals and what dosage we can recommend based on your genetics in order to ensure everything is working alright. Do you remember the gpx1 gene? It needs more selenium so we would recommend more selenium in your diet if you have the genetic variation and normal amounts if you don’t. So here again is information about micronutrients and here you see some scales. You see your requirement of vitamin A. So, it’s actually quite high in this case, vitamin B6 is moderate, vitamin C is a little higher, vitamin E is the same, calcium is lower, iron is quite low, and so on and so forth. All of these vitamins and minerals that are contained in different food types are evaluated here. And we can tell you which amount we would recommend based on your genetics. Omega3 fatty acid in this case will not be recommended. Phytosteral, which is an alternative, is recommended. So this table shows you the recommended day allowance and there are some agencies that try to make recommendations that are applicable to everyone, men and women, children, babies, and they said a person should eat two hundred grams of folic acid applicable to everybody and calcium eight hundred grams and so on. They did their best to try to find out what is the general healthy nutrition, and they did a good job in this respect. But, only through looking at genetics we can see individual differences. And that is why your actual requirement based on your genetics, is deviating from the normal amount. So here you see omega3 fatty acid, we would actually in this case not recommend them because they have a negative effect in some respect and we would recommend phytosterals and so on. So your requirement actually will differ from the actual requirement. And the best way to cover your requirement is to optimize your nutrition, getting the right nutrients from nutrition is always the best approach. So this is what the program is supposed to do, it is trying to find out how much you need, which type of food should you eat to cover these requirements and then you should follow the list and eat the stuff that is recommended and avoid the ones that we don’t recommend and will then help you to get the right nutrition. And these are here scientific references that are built on, everything is very strongly scientifically based, because we are a medical laboratory and we do work with medical genetic standards, so I really claim that we must have a number of scientific studies supporting the same thing. So here you see the scientific studies in case you’re interested. You might need a degree in genetics or medicine to understand some of it but in case you’re interested you can look them up in the internet to find these publications. Now the best way to cover your micronutrients, mineral needs is of course healthy nutrition and this is what this program is meant to help you with, make sure to eat the right food and cover the right nutrients amounts.

Section 13: Personalized Supplement

So you are in the best way of using this program and to make sure you get the right nutrients. However, if you think that you’re not following the program enough or you could do more to get sure you get the right nutrients, there is the option of a personalized supplement. This looks like this. This is one of these bottles and it’s called NutrimeNutrition and the concept works like this: if you open it, it’s a bit difficult to show on camera, but it consists of a lot of different small pellets, small vesicles and we have around twenty different of these pellets and each one of them contains a certain vitamin. So there is one for vitamin C, one for vitamin E and one for vitamin A and so on. What we do is we do know your requirement for different vitamins and we take this information and then we mix the different pellets with different amounts in different concentrations. And then all you do is every morning you take the spoons for as I said I have a high risk of Alzheimer disease I need a lot of antioxidants so I need exactly this amount. I do this in the morning, so I put them in my mouth, drink a glass of water and they’re gone. And they have a number of advantages, as compared to gelatin capsules for example. For example, calcium and zinc, these two substances use the same process of how to be absorbed, so a kind of channels, little doors from the intestine to the blood stream and if you mix calcium and zinc as powders, one of them is going to go through and be absorbed and block the doors and the other one is not going to be absorbed. That’s the general problem, so do look out if you ever see a multi-mineral substance which has both in it because mineral availability is very bad in this case. So the advantage here is these pellets, these small vesicles contain one substance only, so in one position of the intestine you’re going to release calcium and in another position there is going to be a different pellet and you’re going to go really sick, so both are absorbed. Then, this is a slow release, it means over the course of eight hours you’re going to grudge the absorbed vitamins. This is also very important because vitamin C for example has a half-life of half an hour, of thirty minutes, which means if I take one hundred milligrams of vitamin C, and it reaches my blood stream, thirty minutes later half of is already gone, another thirty minutes later half of it would remain, it’s gone so I have a quarter. So especially in the case of vitamin C and antioxidants that our body should have all the time, so whenever a free radical is created that we immediately neutralize, all of these are better in a slow release concept. So it is this slow release that gets your body energy throughout the day, not energy but nutrients, and I prefer to also recommend not to take it at night because it contains vitamin C and for some people, it means especially vitamin C has an invigorating effect so it wakes you up and you might have problem sleeping. So do take it in the mornings or at lunch time and I wouldn’t take it too late at night before going to sleep, but then again you can try it and decide yourself. And this is here on the bottle you will have your name, it’s personally produced for you and here you will see a lot of little scale bars to see how much of each substance is in there. And just to give you an idea, we’ve tested more than fifty genes, more than seven hundred trillion different result possibilities, so this is as unique and personalized as it gets, seven hundred trillion different mixtures. This is not that we have three different ones and you’ve been shipped the best match, everyone is produced specifically for you. The best thing is really the nutrients your body require to keep running, to keep staying healthy. It is recommended to take once per day preferably for the rest of your life. We do take into account the different seasons, if it’s winter you need a little more vitamin D because your body does not produce as much from the sun light and also in different countries it’s a different question. We do take into account increasing age so whenever you order it, it’s re-evaluated. We also take into account new science, when we find out that or it might be better with this genetic variation to actually increase this a bit more if it goes into it. So, every time you reorder we re-evaluated and you get the newest stage of science and it ensures that you have the right nutrients. In order to order this, we have a web site, that’s dnanutricontrol.com web site and there you need to enter a recipe code, because as you remember this is unique based on your genes, so in the report you’re going to find the recipe code. This is how it looks, unfortunately it’s a quite a long code, there’s a lot of information, you’re going to have to integrate this information, enter this information into the form. And this encoded the information that we need to create this, makes it for you. So you order it, and you enter the recipe code and create it and ship it to you and you can just try for three months, you can go for twelve months, and so on. This is the option of how to order this as an additional supplement in case you want to make sure that you get the right nutrients in addition to the right nutrition.

Section 14: The Food table

Let’s now talk about the food table, which is probably the most important or most interesting part of the genetic test. This genetic test is modular, so you do have the chance to say I just want to lose weight or I just want to know what is healthy for me or both of it, together. So depending on which genetic test you’ve ordered, you might see a slightly different food table here. In this example, both of the things were ordered so I can explain all of the aspects of the table. So don’t worry if some of you see a question mark instead of the result here, that’s just because this part was not ordered and it hasn’t been genetically tested. Alright. So now let’s look at the food table, am going to jump over this, you can read it in case you’re interested, am going to explain it on a live table. So let me just find a good page. Over this one, a zoom in. So, first of all here you have different categories of baked goods, cakes and confectionary. So here is the different types of food that all belong to this category. And for one thing, what is important for the weight management aspect in case you have ordered this, you will see these bars here and these bars numbers will likely be different for you because this is based on your genes and it’s all personalized. Something that has less weight-gaining potential than waffles would do, so when a person can eat sixty grams of apple strudel, this would have the same weight gain effect like fifty grams of waffle. So what does this tell you? It tells you eat more apple strudel and less waffles if you have the choice. Both taste maybe the same to you, than you can choose the one that is best for your genes. Some people say looking at these gram numbers is too complicated. They just say I only eat things in the green area and avoid the ones in red, or there might say red only on Sundays otherwise it’s just green. This is a very easy way to adapt your nutrition, it has the benefit of teaching you what type of food is good for you and you like and which ones you should avoid. So this is for the weight management aspect. Go for more green stuff and less red stuff. Also for the weight management stuff, when you look through your table, you will have found something that look like this. Any amount, no item. This means that the calories contained within this food are so insignificant, so small that it doesn’t really matter how much you eat of it. This means in case you’re ever hungry and you don’t have more food to eat because you’ve used up only few items, then you can just look up for these, then eat as much as you want. So for different categories in some cases you’re going to see this quite a lot. So here for example, all different types of salad and so on. So any amount, no item is a good intermediate snack in case you don’t want to gain weight. Now this here shows you the main calorie-containing substances. So for example, spinach. A general portion of spinach is one hundred and fifty grams. And one hundred and fifty grams of spinach contain twenty nine kilo calories, a very low amount, that’s why it’s also a no item, any amount, you can eat that whenever in between. So twenty nine kilo calories is four grams of protein, one gram of carbohydrate and zero grams of fat. These are the important calorie-containing substances. So just in case you’re interested. And if you’re not, as long as you look at these bars, that’s sufficient for your weight loss program. Ok. In case you have an allergy, and you gave us this information at the time of ordering the report, you would see a warning in this area here, so it says allergy and it might show a warning sign. This just means this type of food might contain or is likely to contain a substance that you’ve told us that you’re allergic to. We don’t find allergies from genetics, genetics and allergies are not understood yet. We don’t know how to determine if you’re going to be allergic to something based on a genetic test, so we’re limited with the possibilities here. But if you knew that you are allergic then we could enter this information and it would give you a warning. It doesn’t mean this is a full-proof list, it just means it’s supposed to help you decide and warn you to be careful. It might be that there is something that you’re allergic to. It’s ultimately your responsibility to check every type of food if they contain allergies that you should avoid. It’s just a help but don’t depend on it so much. Then, that’s the weight management aspect. Now for the healthy food aspect, this part here is more important. So, in the first aspect we looked at how much fat, carbohydrates does this contain and what is the weight potential for you. And here we look at all the ingredients that the food has, some of them might be good for you based on your genes and some of them might be bad based on your genes. If there is more good stuff in it, it’s going to be more recommended, it if there is more bad stuff in it, it’s going to be less recommended to you and the mode of recommendation is with these smiling faces, so it’s easy to understand. Six happy smiling faces is the best you can have, it just means that a vegetable mix in general is very healthy for you. It contains a lot of vitamins, minerals that you require in a higher amount based on your genetics and it contains very few problems, very few substances that are a problem for your health. One smiling face is less healthy than six smiling faces. And then neutral faces, these black ones mean it contains negative stuff but also good stuff and it kind of balance each other out so it’s neither good nor bad for you if you read this. And then there is one red smiling face. That means more bad stuff in it than good things and it goes up to seven unhappy faces. So for example, some beans might be very healthy but chickpeas are very unhealthy due to some substances that they contain more. Soybeans are not so good, green peas are better. So, there are really big differences in the same category of food based on more than forty different ingredients or components that this food is made of. And here you can see the components. So, this is just the most important things like the glycaemic index, how lactose is included, how much calcium, how much irons, how much zinc and so on and so different vitamins go on, and we look at all these aspects, look at your genes, we say you have a high a risk of a certain metabolic problem, to counteract it you need a lot of folic acid, how much folic acid is in this type of food, is there anything else that might be bad and in this way we evaluate every one of these types of food independently by looking at all of it together, it’s not just saying fruit is healthy so eat fruit. It’s just too simple. Alright. Even if we look at this table in more detail, you see that some numbers are green, some are black and some are red. Now, these numbers are the same for everyone, so they are not personalized to your genes. It just means that red means a bad substance, sodium for example. This type of food contains a lot of sodium, more than others, that’s why it’s red. So the ones that contain most of red it’s bad and the ones that contain most of something good it’s green. So, the green numbers mean it’s particularly rich in folic acid and this is particularly rich in sodium. It might help you to get a little insight into why something might be less healthier, more healthier for you. However, as I said it’s a very complicated thing, every one of these types of food has at least five hundred different calculations being done and different factors being considered, and overall if it’s beneficial or bad for you is considered in this. So, this is for people that are really interested in how much of each of these substances is contained within, but you don’t need to know the deep works or how it works. For you to use really it’s just eat more of the green smileys, eat less of the red smileys, and the unhappy faces. And sometimes you might even see in meat all of it is bad, some of it has six red smileys red unhappy faces, and some of it has two. So you should just refer the ones with less unhappy faces and you should generally eat less of the stuff that is red and more of the stuff that is green. This doesn’t mean that you can never eat anything with red but make it an exception rather than a rule. For weight management as I said just look at the bars, maybe use the grams bar item, it might be answers per item depending on where you’re located. And here is one more aspect. You see as well lactose, gluten and caution. And this means if for example you are genetically predisposed to be lactose intolerant then it doesn’t mean you are lactose intolerant it just means you are likely to develop lactose intolerant symptoms at some point in your life. It also does not mean you should stop eating lactose-containing milk products unless you have symptoms. So there is no need to stop eating. It just means you might have a warning sign here some time, you can eat this type of food but if you ever get bad reaction remember check out if you have a warning here, if yes then it’s likely that you have developed a food intolerance that you have a genetic predisposition to. The same goes for gluten. So you can continue eating it if there is a warning sign, but if you realize you have a bad reaction then avoid everything with the warning. That is as simple as that, because it will help you deal with lactose intolerance and gluten intolerance in a very simple way. It’s similar with the caution. So if you have a caution sign in here it just means you can eat this type of food but it might at some point cause problems, so just look out for and if you ever get a bad reaction avoid everything that has the caution sign. It’s as simple as that. So really it helps you avoid any type of food that is bad for you or that might cause digestive problems.

Section 15: Certifications and Technical Details

Alright. This here at the end is quite technical in case you’re interested, otherwise you can skip this last part. This is just information about our certification. Now what sets us apart from other suppliers of genetic testing is that we have our own in-house laboratory, so we run our own laboratory, our own processes and we put a very high focus on high quality, documentation, high certifications. So we’ve lots of external bodies coming in and auditing us, auditing our data protection system, auditing our quality management system and so on and we also want to have control over the quality as well as a very high level of automation. If you’re interested, there is in the internet showing the level of automation. All of our processes are done by robots and machines to avoid human errors and improve throughput and here I am just quickly going to walk you through the certifications that we have in our laboratory. So for one thing, this here is from the Austrian state and many countries have genetic testing laws which are meant to protect consumers from discrimination against genetics and so on. And they are in a different form in different countries and as far as am aware Austria in Europe has the most strict genetic testing laws that am aware of. So we have the license to perform medical genetic testing, issued by the Austrian government. So they came, they audited the laboratory and they do this on a regular basis and a very strict process of obtaining this license to perform medical genetic tests. So this is the first certification we have. Then, in addition, this one is compulsory to have a laboratory in Austria, it’s also a quality sign compared with other countries where you can do it without any kind of such certification. So, this is one of the steps. And then the optional certification, the ISO one five one eight nine, is the highest level of quality certification you can have for a medical laboratory. So it looks for quality control, it checks for errors, validation of processes and so on. And this certification applies to lifestyle analysis for weight management and healthy nutrition as well as for medical interpretation of genetic analysis, and the company office is ISO nine thousand and one certified. This is all about document control, continuing improvement and so on. Then, some of the medical genetic analyses are covered, not by one five one eight nine, but by ISO one seven zero two five, it’s similar to the ISO one five one eight nine, but it’s slightly different. So all processes are highly certified, audited not only by us, by our own quality management team but also by some of the companies we supply as well as government bodies and official certifications institutions. This here it just shows technical details, so order number, date of birth, the analyzing laboratory address, my signature again for releasing your genetic results, because every genetic result needs to be looked up by three people, two different scientists that analyze the results and then we compare if they both have the same conclusion, if yes we can go ahead, and then my signature as a laboratory head to release the results for shipping. And then some other information of when the analysis time have been performed.

Section 16: Closure

Alright, then. This is the end of this counselling session, I hope you found it interesting and I hope I cleared up any misunderstanding that you might have had. I did my best to explain everything. Do read through the book again and it will explain, it will repeat a lot of the things that I have said and I think it will make some things more clear. The ones that are scientifically very interested will find enough basis for research into the science behind the whole program and I hope we made it very transparent of what scientific studies everything is based on, that I have convinced you of the scientific basis of this program. I hope I have also given you a number of different options of how to use this program to your liking, some people want to do it online, some people want to do it on paper, some people want to do it easy, and others want flexibility. So I think you’ve seen that you have lots of different options of how to use the program and I think there isn’t much left to say in case you do have questions do contact us we’ll do our best to answer those questions and also try to improve the texts in the reports to make sure that future customers do understand them correctly, so please do get back to us. We like positive as well as negative feedback to improve our system in the future. And there is nothing left for me to say other than to wish you a lot of success for your nutrigenetic program (end).